They are safe to take it together but be sure to look at all the ingredients on the specific Mucinex product you room purchasing.

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Gerry asked

I newly came down through a cold and also wanted to understand whether or not there is an interaction in between Mucinex and also Sudafed.

At a glance

Sudafed (pseudoephedrine) deserve to safely it is in taken through Mucinex (guaifenesin). However, be careful of Mucinex products that contain more than one ingredient and make sure they don"t currently contain a sleep decongestant (i.e. Pseudoephedrine or phenylephrine).


Yes, you deserve to safely take Mucinex (guaifenesin) through Sudafed (pseudoephedrine) as there is no interaction in between them. In fact, both drugs can be found linked in a single product, Mucinex-D, which is easily accessible behind the pharmacy counter.

It is crucial to keep in mind that there room severalMucinex assets on the market. Castle include:

Mucinex (guaifenesin)Mucinex D (guaifenesin; pseudoephedrine)Mucinex Fast-Max severe Congestion and also Cough (guaifenesin; dextromethorphan; phenylephrine)Mucinex Fast-Max Cold, Flu and also Sore neck Congestion and also Cough(guaifenesin; acetaminophen; dextromethorphan; phenylephrine)Mucinex Sinus-Max (guaifenesin; acetaminophen; phenylephrine)

You don"t desire to integrate Sudafed v a Mucinex product the alreadycontains a decongestant. The two decongestants to stop doubling up on are:


So, to it is in specific, Sudafed is for sure to take it with just two Mucinex products:

Mucinex (guaifenesin)Mucinex DM (guaifenesin; dextromethorphan)

All other Mucinex products alreadycontain a decongestant. Taking as well high of a dose of a decongestant deserve to increase the threat of side effects, such as:

Increased blood pressureInsomniaSweatingIncreased love rateRestlessness

The following sections carry out some added information concerning guaifenesin, pseudoephedrine, and also phenylephrine.

About Guaifenesin

Guaifenesin is an oral expectorant, generally used come treat cough as result of colds and also minor top respiratory infections. It help to loosen and also thin mucus and bronchial secretions by to reduce both your viscosity and also adhesiveness. This provides secretions simpler to expectorate and also remove.

Guaifenesin is a common ingredient in numerous over the respond to products and is accessible in both immediate and also extended-release formulations.

About Pseudoephedrine

Sudafed (pseudoephedrine) is a nasal decongestant that is also used to relieve sinus push in adults and also children 4 years of age and also older. Immediate release assets work quickly, in ~ 15-30 minutes. The usual duration of action is 4-6 hrs although 12 and also 24-hour formulations are also available.

Unlike plenty of nasal decongestant sprays (e.g. Afrin), Sudafed does not typically reason rebound congestion and can often be safely take away for much more than 3 days.

As a result of the 2005 Combat Methamphetamine Epidemic Act,pseudoephedrine need to be locked securely or stored behind the pharmacy counter.

About Phenylephrine

Phenylephrine is nasal decongestant obtainable over the counter. It is accessible as a single ingredient (phenylephrine) or in combination with other medications in miscellaneous cough/cold products.

It works to alleviate congestion by constricting the blood vessels in the nose, reduce inflammation and also opening the airways.

It may be taken v or there is no meals and also reaches optimal concentrations about 1-2 hours after taking by mouth. The term of action of the drug is approximately 4 to 6 hours.

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Unlike pseudoephedrine, phenylephrine go not have to be save behind the pharmacy counter.